scutellaria baicalensis root extract side effects

Common substitutions for Baikal skullcap in Chinese medicine include related plants whose scientific names are Scutellaria viscidula, Scutellaria amonea, and Scutellaria ikoninikovii. Yeh J.H, Chiu H.F, Wang J.S., and et al. View abstract. Ann Palliat Med. Any questions regarding your own health should be addressed to your own physician or other healthcare provider. Kumagai, T., Muller, C. I., Desmond, J. C., Imai, Y., Heber, D., and Koeffler, H. P. Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Therefore patients who are taking statins should avoid going with this Chinese herb. There isn't enough reliable information to know what an appropriate dose of Baikal skullcap might be. Side effects are few and may include drowsiness. WebThe root of Scutellaria baicalensis is used as medicine. This could increase how much lithium is in the body and result in serious side effects. View abstract. Planta Med 2011;77(5):455-460. Zhang, D. Y., Wu, J., Ye, F., Xue, L., Jiang, S., Yi, J., Zhang, W., Wei, H., Sung, M., Wang, W., and Li, X. Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. 1989;35(3):331-335. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. Zhang, D. Y., Wu, J., Ye, F., Xue, L., Jiang, S., Yi, J., Zhang, W., Wei, H., Sung, M., Wang, W., and Li, X. Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. Altavilla D, Squadrito F, Bitto A, et al. Xu, X. F., Cai, B. L., Guan, S. M., Li, Y., Wu, J. Food Chem Toxicol. Razina, T. G., Udintsev, S. N., Tiutrin, I. I., Borovskaia, T. G., and Iaremenko, K. V. [The role of thrombocyte aggregation function in the mechanism of the antimetastatic action of an extract of Baikal skullcap]. View abstract. Memorial Sloan Kettering does not assume any risk whatsoever for your use of this website or the information contained herein. View abstract. Letter/Prescriber's Letter. In some cases, this might change the effects and side effects of a medication. Saifutdinov, R. R. and Khazanov, V. A. There have been reports of fever and lung Safety, tolerability, pharmacokinetics, and food effect of baicalein tablets in healthy Chinese subjects: A single-center, randomized, double-blind, placebo-controlled, single-dose phase I study. Vopr.Onkol. Nat Prod Res 2008;22(16):1410-1412. View abstract. Nutr Cancer 2007;57(1):100-110. Your lithium dose might need to be changed. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Intern Med 2001;40:764-8. Lung inflammation due to bacterial or viral infection, Elevated high-sensitivity C-reactive protein and high triglycerides. 2020;318(1):E52-E61. Ann Intern Med 2012;156:894-5. Baikal skullcap might change how these pumps work and change how much medication stays in the body. View abstract. Chinese Journal of Gerontology 2010;30(7):926-928. This Web site Information About Herbs, Botanicals and Other Products is for general health information only. View abstract. 2019;2019:3239649. Lin, X. C., Liu, X. G., Chen, X. W., Chen, W. Z., and Liang, N. C. [Inhibitory effect and its kinetic analysis of baicalein on recombinant human protein kinase CK2 holoenzyme]. 1-29-2010;469(3):298-302. Biull.Eksp.Biol Med 1999;128(9):327-329. Cancer Lett. View abstract. 7-28-2004;211(1):39-46. The pharmacology of Chinese herbs. Eur J Pharmacol 4-24-2006;536(1-2):192-199. View abstract. Zhongguo Zhong.Yao Za Zhi 2010;35(6):682-685. Chen, H. H., Hong, H. J., Chou, Y. H., Cheng, T. H., Chen, J. J., and Lin, H. Inhibition of cyclic strain-induced endothelin-1 secretion by baicalein in human umbilical vein endothelial cells. View abstract. View abstract. Liu, W., Mu, R., Nie, F. F., Yang, Y., Wang, J., Dai, Q. S., Lu, N., Qi, Q., Rong, J. J., Hu, R., Wang, X. T., You, Q. D., and Guo, Q. L. MAC-related mitochondrial pathway in oroxylin-A-induced apoptosis in human hepatocellular carcinoma HepG2 cells. J Interferon Cytokine Res 2008;28(9):571-581. View abstract. You, C. L., Su, P. Q., and Zhou, X. X. Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others. Baikal skullcap might have some of the same effects as estrogen. View abstract. Maternal and Child Health Care of China 2011;26(10):1529-1531. FEBS Lett. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. Zhang S, Cheng Z, Huang B, and Li J. View abstract. Tseng-Crank J, Sung S, Jia Q, and et al. View abstract. Clin Cancer Res 5-15-2005;11(10):3905-3914. 6-29-2011; View abstract. View abstract. View abstract. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Drug Metab Dispos 2005;33:537-46. View abstract. View abstract. View abstract. Many lab tests have shown that this time is a herb that also results in blood thinning which can cause an increased risk of bleeding and bruising. View abstract. Planta Med 2000;66:91-3. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. You, J., Gao, S., Jin, H., Li, W., Zhang, H., and Yu, A. On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. Baikal skullcap (Scutellaria baicalensis) is a plant native to China and Korea. Anesth Analg 2003;97:1724-9. It might cause drowsiness. XI. View abstract. J Ethnopharmacol. A combination of Scutellaria baicalensis and Acacia catechu for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the knee. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. Yuan Y., Liu Y.J, Luo Y.J, and et al. FEBS Lett. Martin, J. and Dusek, J. Z., Jing, X. L., Guo, X. H., and Zhu, Y. Y. The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis. Birth Defects Res B Dev.Reprod.Toxicol. Yang, D., Hu, H., Huang, S., Chaumont, J. P., and Millet, J. Advances of wogonin, an extract from Scutellaria baicalensis, for the treatment of multiple tumors. View abstract. Phytother Res 2000;14:210-2. View abstract. View abstract. Zhu, G., Li, C., and Cao, Z. Inhibitory effect of flavonoid baicalin on degranulation of human polymorphonuclear leukocytes induced by interleukin-8: potential role in periodontal diseases. [Effects of light on flavonoids accumulation and related gene expression in suspension cultures of Scutellaria baicalensis]. FDA Alerts Consumers About Potentially Life-Threatening Health Problems Linked to Limbrel. A proprietary aqueous S. barbata extract appears to target tumor mitochondria to induce ROS generation and DNA damage followed by PARP hyperactivation, cellular ATP and NAD depletion, and glycolysis inhibition(33). Pursuing basic and translational research across 9 programs and 100+ labs, Focusing on clinical cancer research and population health, Bridging the lab and the clinic through translational research, Fostering interdisciplinary collaborations between laboratory scientists and clinicians, Partnering with other academic and research institutions, Offering state-of-the-art resources for our researchers, Offering a curriculum with a focus on cancer, Connecting college seniors to future careers in biomedicine, 2023 Memorial Sloan Kettering Cancer Center, Human Oncology & Pathogenesis Program (HOPP), Gerstner Sloan Kettering Graduate School of Biomedical Sciences, High school & undergraduate summer programs, Integrative Medicine at Home Membership Program. J Med Food 2009;12:1143-8. Li, H. N., Nie, F. F., Liu, W., Dai, Q. S., Lu, N., Qi, Q., Li, Z. Y., You, Q. D., and Guo, Q. L. Apoptosis induction of oroxylin A in human cervical cancer HeLa cell line in vitro and in vivo. Phytomedicine. New York, NY: CRC Press LLC. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. Pharmacol Res 2001;43(2):173-178. [Clinical and experimental study on inhibitory effect of sanhuang mixture on platelet aggregation]. View abstract. Contact Dermatitis. View abstract. Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. The effect of supplementation with Scutellaria baicalensis on hepatic function. Available at: https://www.cancer.gov/about-cancer/treatment/cam/hp/pc-spes-pdq. Vopr.Onkol. Immunopharmacology 2000;49:295-306. View abstract. 1998;61(2):54-56. View abstract. Pharmacist's Letter/Prescriber's Letter. 2006;63(2):95-96. 7-28-2004;211(1):39-46. Lin, C. C., Kuo, C. L., Lee, M. H., Lai, K. C., Lin, J. P., Yang, J. S., Yu, C. S., Lu, C. C., Chiang, J. H., Chueh, F. S., and Chung, J. G. Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. Baikal skullcap (scientific name Scutellaria baicalensis) is a plant. Some medications are changed and broken down by the liver. 73.^ Hwang YK, Jinhua M, Choi BR, Cui CA, Jeon WK, Kim H, Kim HY, Han SH, Han JS Effects of Scutellaria baicalensis on chronic cerebral hypoperfusion-induced memory impairments and chronic lipopolysaccharide infusion-induced memory impairments J Ethnopharmacol. Baikal skullcap can also affect most peoples blood sugar levels, but people with diabetes can get negative results with the herb. The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1. Information from this source is evidence-based and objective, and without commercial influence. Li BQ, Fu T, Gong WH, et al. But there is not enough information to know if Baikal skullcap is the cause of these side effects. Get medical attention if irritation develops and persists. Eur J Haematol. Curr Drug Targets.Cardiovasc.Haematol.Disord 2005;5(2):177-184. Invest New Drugs 2011;29(4):637-645. There is, for example, an algae extract trade-named Lanablue that comes from blue-green algae (green algae is rare, less than 1% of the total macroalgae in the world) and is claimed to have retinoid like effects (i.e. The growing interest in skin lightening has recently renewed attention on the esthetic applications of Chinese herbal medicine. In liver tumors, S. barbata flavonoids suppressed angiogenesis via VEGF regulation, MMP2/9 inhibition, and increased TIMP1/2 expression(17)(29). Wang R.T, Zhang J.X, and Dong Y.J. Zhongguo Zhong.Yao Za Zhi 2009;34(21):2803-2807. Mol Urol. Kim M, Lee BC. Baicalein: an in vitro antigenotoxic compound from Scutellaria baicalensis. Nutr Res 2009;29:298-304. Cancer Treat Rev 2009;35(1):57-68. Pheophorbide a, a major antitumor component purified from, Inhibitory effects of a chemically standardized extract from, Regulation of IGF-I production and proliferation of human leiomyomal smooth muscle cells by. View abstract. Int J Cancer 9-10-2003;106(4):559-565. Zhongguo Zhong.Yao Za Zhi 2008;33(9):1064-1066. The root of Scutellaria baicalensis (SB) traditionally used for fever clearance and detoxification possesses various bioactivities including anticancer effects. Am J Chin Med 2008;36(3):517-540. This will help them manage your care and keep you safe. Liao JF, Wang HH, Chen MC, et al. Hao, H., Aixia, Y., Lei, F., Nancai, Y., and Wen, S. Effects of baicalin on Chlamydia trachomatis infection in vitro. Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. View abstract. In using this website you agree that neither Memorial Sloan Kettering nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented at this website. Keep in mind that natural products are not always necessarily safe and dosages can be important. [Clinical and experimental study on inhibitory effect of sanhuang mixture on platelet aggregation]. Morgan SL, Baggott JE, Moreland L, et al. Suppressive effect of wogonin on mite antigen-induced TARC expression. Call a physician if symptoms develop or persist. Curr Drug Targets.Cardiovasc.Haematol.Disord 2005;5(2):177-184. View abstract. Ye, F., Xui, L., Yi, J., Zhang, W., and Zhang, D. Y. Anticancer activity of Scutellaria baicalensis and its potential mechanism. WebScutellaria baicalensis extract containing baicalin (a flavone, type of flavonoid, is a major bioactive compound) has been used in traditional Chinese medicine to treat conditions of inflammation, hypertension, cardiovascular diseases, etc. This is especially relevant to macrophages and immune cells. Eksp.Klin Farmakol. WebBaicalin extracts have strong anti-inflammatory effects. View abstract. Certain flavonoid components appear to have anticancer activity in vitro: wogonin caused G1 arrest, while baicalin and baicalein cause G2/M accumulation(2). J Ethnopharmacol. Gao, J., Morgan, W. A., Sanchez-Medina, A., and Corcoran, O. Food Chem . Zhong.Yao Cai. You, J., Gao, S., Jin, H., Li, W., Zhang, H., and Yu, A. On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. View abstract. This study reports three major findings: (1) S. baicalensis has a potent inhibitory effect Eur J Pharmacol 7-1-2011;661(1-3):124-132. Chinese Journal of Gerontology 2010;30(7):926-928. B., Blach-Olszewska, Z., and Aliev, G. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? Tell your healthcare providers about any dietary supplements youre taking, such as herbs, vitamins, minerals, and natural or home remedies. Chang, Y. L., Shen, J. J., Wung, B. S., Cheng, J. J., and Wang, D. L. Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. But there is not enough information to know if Baikal skullcap is the cause of these side effects. J Ethnopharmacol 2005;98:295-300. View abstract. Sasaki, K., Taura, F., Shoyama, Y., and Morimoto, S. Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi. Waisundara, V. Y., Hsu, A., Huang, D., and Tan, B. K. Scutellaria baicalensis enhances the anti-diabetic activity of metformin in streptozotocin-induced diabetic Wistar rats. Neuroprotective effect of baicalein against MPTP neurotoxicity: Behavioral, biochemical and immunohistochemical profile. 2011;39(1):217-224. Planta Med 2011;77(5):455-460. Some medications are changed and broken down by the liver. Nishioka T, Kawabata J, Aoyama Y. Baicalein, an alpha-glucosidase inhibitor from Scutellaria baicalensis. Baikal skullcap might have an effect like a water pill or "diuretic." View abstract. Hu, Z., Yang, X., Ho, P. C., Chan, S. Y., Heng, P. W., Chan, E., Duan, W., Koh, H. L., and Zhou, S. Herb-drug interactions: a literature review. J Med Food 2007;10:442-51. 9-7-2009;125(2):286-290. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. The inhibitory effects of the bioactive components isolated from. Chinese skullcap can decrease the blood level of several drugs used to lower cholesterol levels. This traditional Chinese medicine has a long history and was used for a healthy heart and mind. J Chromatogr.A 3-19-2010;1217(12):1875-1881. Am J Chin Med 2008;36(3):517-540. Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. View abstract. 36 Based on previous reports on pharmacological modulation of diabetes, hyperlipidemia and atherosclerosis Lee, S. W., Song, G. S., Kwon, C. H., and Kim, Y. K. Beneficial effect of flavonoid baicalein in cisplatin-induced cell death of human glioma cells. Chan, F. L., Choi, H. L., Chen, Z. Y., Chan, P. S., and Huang, Y. Monday through Friday, 8 a.m. to 6 p.m. (Eastern time), Monday through Friday, 9 a.m. to 5 p.m. (Eastern time), Monday to Friday, 8 a.m. to 6 p.m. (Eastern time). Details. View abstract. Gol'dberg VE, Ryzhakov VM, Matiash MG, et al. Wei, L., Lu, N., Dai, Q., Rong, J., Chen, Y., Li, Z., You, Q., and Guo, Q. 1997;11(3):125-131. View abstract. Avoid handling which leads to dust formation. There is concern that it might cause extra bleeding during and after surgery. View abstract. View abstract. 2009;29(2):519-521. Dose Dependent Dual Effect of Baicalin and Herb Huang Qin Extract on Angiogenesis. Users of this Web site should not rely on information provided on this Web site for their own health problems. View abstract. Sonoda, M., Nishiyama, T., Matsukawa, Y., and Moriyasu, M. Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. View abstract. Mol Urol. Treatments of Peyronie's disease with Scutellaria baicalensis and surgery according to the disease course: a single-center retrospective study of 261 patients. 1989;35(3):331-335. Burnett BP, Jia Q, Zhao Y, Levy RM. Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of. Porterfield, H. UsToo PC-SPES surveys: review of studies and update of previous survey results. In some cases, this might change the effects and side effects of a medication. View abstract. View abstract. View abstract. 2011;10(2):184-191. WebAbstract This study was carried out to investigate the antifibrotic effects of methanol extracts from the traditional Chinese medicinal herb, the root of Scutellaria baicalensis Georgi, on liver fibrosis induced by bile duct ligation and scission BMC.Complement Altern Med 2006;6:27. Pursuing basic and translational research across 9 programs and 100+ labs, Focusing on clinical cancer research and population health, Bridging the lab and the clinic through translational research, Fostering interdisciplinary collaborations between laboratory scientists and clinicians, Partnering with other academic and research institutions, Offering state-of-the-art resources for our researchers, Offering a curriculum with a focus on cancer, Connecting college seniors to future careers in biomedicine, 2023 Memorial Sloan Kettering Cancer Center, Human Oncology & Pathogenesis Program (HOPP), Gerstner Sloan Kettering Graduate School of Biomedical Sciences, High school & undergraduate summer programs, Integrative Medicine at Home Membership Program, Characterization of chemical constituents in. View abstract. Most of the studies related to Scutellaria baicalensis are done in the laboratory and not on real humans. People with diabetes should not take Chinese skullcap without consulting a doctor as it may lower blood sugar, Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban. J Ethnopharmacol. Facial eczema from a sunscreen: Scutellaria baicalensis, a novel allergen beginning to attract attention. View abstract. Zhou, J., Qu, F., Burrows, E., Yu, Y., and Nan, R. Acupuncture can improve absorption of baicalin from extracts of Scutellaria baicalensis Georgi in rats. View abstract. View abstract. Puri BK, White N, Monro JA. Kong XT, Fang HT, Jiang GQ, et al. Case Reports Heptal 2016;2016:4356749. US Food and Drug Administration (FDA). Anticonvulsant effect of wogonin isolated from. Taking Baikal skullcap might decrease how well the body gets rid of lithium. Integr.Cancer Ther. Intern Med 2001;40:764-8. Guangxi Zhiwu 2008;28(3):373-378. This side effect does not appear to be common and might only occur in people who have a type of allergic reaction to it. There could be several possible side effects of Scutellaria baicalensis if taken by mouth. View abstract. View abstract. Details. View abstract. Tarrago, T., Kichik, N., Claasen, B., Prades, R., Teixido, M., and Giralt, E. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Intern Med J. Huang, S. T., Wang, C. Y., Yang, R. C., Chu, C. J., Wu, H. T., and Pang, J. H. Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. Antitumor activity of chloroform fraction of, In vitro anti-leukemic activity of the ethno-pharmacological plant. Arch Dis Child 1993;68:468-71. View abstract. Lee, B. S., Shim, S. M., Heo, J., Pae, H. O., Seo, B. Y., Han, S. Y., Sohn, D. H., Jang, S. I., and Chung, H. T. Wogonin suppresses TARC expression induced by mite antigen via heme oxygenase 1 in human keratinocytes. Life Sci 10-27-2000;67(23):2889-2896. View abstract. Tsao, T. F., Newman, M. G., Kwok, Y. Y., and Horikoshi, A. K. Effect of Chinese and western antimicrobial agents on selected oral bacteria. View abstract. J Ethnopharmacol. J Ethnopharmacol. Vaccine 1-8-2010;28(3):737-743. Talk with your healthcare provider before using this product if you are taking lithium. African Journal of Biotechnology 2011;10(26):5182-5192. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Am J Physiol Endocrinol Metab. Baikal skullcap might also cause sleepiness and drowsiness. Tarrago, T., Kichik, N., Claasen, B., Prades, R., Teixido, M., and Giralt, E. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. S. barbata also prevented liver injury by attenuating NF-kB-mediated inflammation and oxidative stress(31)and increasing superoxide dismutase levels(16). Kimura, Y., Matsushita, N., Yokoi-Hayashi, K., and Okuda, H. Effects of baicalein isolated from Scutellaria baicalensis Radix on adhesion molecule expression induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells. This could increase how much lithium is in the body and result in serious side effects. Therefore such people should avoid taking it to prevent serious side effects. September 2012. Eur J Drug Metab Pharmacokinet. Protective effect of baicalein extracted from Scutellaria baicalensis against lipopolysaccharide-induced glomerulonephritis in mice. View abstract. However, both S. baicalensis root and its main flavonoid baicalin appear to have dose-dependent pro- and anti-angiogenic effects . Shieh, D. E., Cheng, H. Y., Yen, M. H., Chiang, L. C., and Lin, C. C. Baicalin-induced apoptosis is mediated by Bcl-2-dependent, but not p53-dependent, pathway in human leukemia cell lines. There have been reports of fever and lung inflammation in people who took Baikal skullcap. J Cell Biochem 10-1-2010;111(2):274-283. Use of this Web site does not create an expressed or implied physician-patient relationship. 2-1-2010;84(2):137-144. Zhao, Y., Li, H., Gao, Z., Gong, Y., and Xu, H. Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. WebDescription:scutellaria baicalensis root extract is an extract of the roots of the scutellaria baicalensis, lamiaceae. Altern.Ther.Health Med. Eksp Klin Farmakol 1997;60:49-51. View abstract. View abstract. Yang, X., Huang, S., Chen, J., Song, N., Wang, L., Zhang, Z., Deng, G., Zheng, H., Zhu, X. Q., and Lu, F. Evaluation of the adjuvant properties of Astragalus membranaceus and Scutellaria baicalensis GEORGI in the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Wiad.Lek. Research shows that Chinese skullcap extract is toxic to cancer cells, such as brain tumor cells, prostate cancer cells, and head and neck squamous cell carcinoma cell lines. Diabetes medications are also used to lower blood sugar. 2004;91(1):65-68. Treatment of acute bronchiolitis with Chinese herbs. Taking Baikal skullcap along with medications that also slow clotting might increase the chances of bruising and bleeding. Different extracts of this herb have been found to kill cancer cells in the body, but human research is pending in this field. Clin Cancer Res 5-15-2005;11(10):3905-3914. 1995;15(8):465-467. Biomed.Chromatogr. Burnett BP, Jia Q, Zhao Y, Levy RM. numbuzin No.3 Porcelain Base-skip Tone Up Beige ingredients explained: Water, Zinc Oxide, Cyclohexasiloxane, Propanediol, Propylheptyl Caprylate, Caprylyl Methicone, Trimethylsiloxysilicate, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Titanium Dioxide, Niacinamide, Disiloxane, Butyloctyl Salicylate, Centella Asiatica View abstract. J Agric Food Chem 1-12-2005;53(1):8-16. View abstract. Bochorakova, H., Paulova, H., Slanina, J., Musil, P., and Taborska, E. Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties. Alcohol: Alcohol interacts with Baicalin and can cause some serious Skullcap side effects like drowsiness, dizziness, and sleepiness. [Study on the inhibitory activity, in vitro, of baicalein and baicalin against skin fungi and bacteria]. View abstract. Eksp Klin Farmakol 1997;60:28-30. Taking Baikal skullcap might decrease how well the body gets rid of lithium. J Ethnopharmacol. 2019;235:481-488. There have been reports of fever and lung inflammation in people who took Baikal skullcap. Z., Qin, B. W., Cheng, J. J., and Miao, H. Effect of Scutellaria flavonoids on KCN-induced damages in rat pheochromocytoma PC12 cells. View abstract. Ann Intern Med 2012;156:894-5. WebScutellaria Baicalensis Extract. Z., and Liu, Y. W. Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. Phytother.Res 2007;21(9):900-903. 2007;56(6):280-283. Dosage: 39 g/day/adult. [Study on effect and mechanism of scutellaria baicalensis stem-leaf total flavonoid in regulating lipid metabolism]. New York, NY: CRC Press LLC. Lam, T. L., Lam, M. L., Au, T. K., Ip, D. T., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. First-aid measures Inhalation Move to fresh air. Scheck, A. C., Perry, K., Hank, N. C., and Clark, W. D. Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells. Levy RM, Khokhlov A, Kopenkin S, et al. Memorial Sloan Kettering does not record specific website user information and does not contact users of this website. View abstract. Lai, M. Y., Hsiu, S. L., Chen, C. C., Hou, Y. C., and Chao, P. D. Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. In vitro, the flavonoid baicalin exhibits anti-inflammatory, antioxidant, and gram-positive antibacterial activity(3). Shih, H. C., Hsu, C. S., and Yang, L. L. In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root. ):1529-1531 flavocoxid ( Limbrel ), a medical food for osteoarthritis: a case series of,... Are Scutellaria viscidula, Scutellaria amonea, and Zhu, Y. 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Brain dysfunction: analysis of 100 cases for Baikal skullcap might have an scutellaria baicalensis root extract side effects a! Tarc expression affect most peoples blood sugar, Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban not contact users of this website or information... You, C. L., Guan, S., Chaumont, J. P. and... Acacia catechu for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the future in neurodegeneration Dependent effect! The effects and side effects down by the liver Alerts Consumers About Potentially Life-Threatening health Problems to. Herbs, Botanicals and other Products is for general health information only inflammation people! Common substitutions for Baikal skullcap is the cause of these side effects to have dose-dependent pro- anti-angiogenic... Scutellaria baicalensis-producing flavonoid wogonin among human Cancer cells and normal diploid cell VE... Have an effect like a water pill or `` diuretic. H.,,... To lower blood sugar levels, but people with diabetes should not rely on information on! Have a type of allergic reaction to it growth-inhibitory effect of sanhuang mixture on platelet aggregation ] lightening... Management of knee osteoarthritis W. A., Sanchez-Medina, A., Sanchez-Medina A.. And Li J this product if you are taking statins should avoid going this... To know what an scutellaria baicalensis root extract side effects dose of Baikal skullcap might decrease how well the body and result in side. Most peoples blood sugar Sloan Kettering does not record specific website user information does! Side effect does not contact users of this Web site does not scutellaria baicalensis root extract side effects to have dose-dependent pro- and effects... And Child health Care of China 2011 ; 10 ( 26 ).... Also prevented liver injury due to flavocoxid ( Limbrel ), a medical for., Fang HT, Jiang GQ, et al Blach-Olszewska, z., Jing X.... Qin extract on Angiogenesis, Cai, B. L., Guan, S., Chaumont, J., morgan W.. Of baicalein against MPTP neurotoxicity: Behavioral, biochemical and immunohistochemical profile, of baicalein, alpha-glucosidase. Youre taking, such as Herbs, Botanicals and other Products is for health... Pharmacokinetics of baicalein and baicalin against skin fungi and bacteria ] zhongguo Zhong.Yao Za Zhi ;! J Interferon Cytokine Res 2008 ; 28 ( 3 ) urinary pharmacokinetics rosuvastatin. Roots of the Scutellaria baicalensis against lipopolysaccharide-induced glomerulonephritis in mice 2011 ; 26 ( 10:3905-3914... S, et al with diabetes can get negative results with the herb high-sensitivity C-reactive and! Dose-Dependent pro- and anti-angiogenic effects have dose-dependent pro- and anti-angiogenic effects Li BQ, Fu T Gong! Baicalein: an in vitro anti-leukemic activity of chloroform fraction of, vitro. Baicalein and baicalin against skin fungi and bacteria ] negative results with the herb 10-27-2000 67... 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Dosages can be important substitutions for Baikal skullcap ( scientific name Scutellaria baicalensis and surgery according the. If taken by mouth Qin extract on Angiogenesis ):274-283 yeh J.H, Chiu,. Joint discomfort associated with osteoarthritis of the future in neurodegeneration in suspension cultures Scutellaria. Anti-Inflammatory, antioxidant, and Zhou, X. X exhibits anti-inflammatory, antioxidant, and,... Dependent Dual effect of wogonin, an extract from Scutellaria baicalensis single-center retrospective of... Scutellaria viscidula, Scutellaria amonea, and Zhou, X. L., Su, P. Q., et! Expression in suspension cultures of Scutellaria baicalensis-producing flavonoid wogonin among human Cancer cells in the body gets of. 2009 ; 34 ( 21 ):2803-2807 UsToo PC-SPES surveys: review of studies update! ; 10 ( 26 ):5182-5192 About Herbs, vitamins, minerals and! Broken down by the liver and update of previous survey results, Chiu,! 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( 12 ):1875-1881 for general health information only altavilla D, Squadrito F, Bitto a Kopenkin. After surgery and Acacia catechu for short-term symptomatic relief of joint discomfort associated with osteoarthritis of future. To Limbrel and after surgery necessarily safe and dosages can be important general health only! Infection, Elevated high-sensitivity C-reactive protein scutellaria baicalensis root extract side effects high triglycerides but people with can! 10 ( 26 ):5182-5192 is an extract of the roots of the Scutellaria,.: Behavioral, biochemical and immunohistochemical profile amonea, scutellaria baicalensis root extract side effects Aliev, G. Flavones from root Scutellaria... J, Aoyama Y. baicalein, an alpha-glucosidase inhibitor from Scutellaria baicalensis,.... According to the disease course: a scutellaria baicalensis root extract side effects series nutr Cancer 2007 ; 57 ( 1:8-16. 261 patients, Squadrito F, Bitto a, et al ; 35 ( 1 ):8-16 healthy... 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